Used RODI setup and pipes in walls humming

Do you have any way to check the water pressure?  You should be at 80psi or below.   Could be the back pressure from running the RO is causing it.
 
You should have a water pressure reducing valve between your house and the city water line.   Mine is in the front of the house in the bushes.  It looks like a smaller version of the main valve that is out by the street that the city uses to turn your water on/off.   You tube has plenty of videos on how to adjust it.
 
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