How does it work? Do you do it to all of your salt water?"]
Prime is very concentrated, so you use very little. I have always added Prime to all my top off water, and salt water changes, even if it is RO/DI water. I use a 1 ml, or 5ml syringe to add Prime. 1ml for every 10 gallons is all that you need. If for some reason the water treatment plant adds excessive ammonia to the water, or if the salt mix has a trace of ammonia, I am covered, and Prime is cheap, and is supposed to add a protective slime coat to your fish. Since your water goes though RO/DI filtration, that takes out some ammonia, you can probably use half a dose of Prime. A full dose removes about 1 mg/l ammonia, 4 mg/l chloramine, and 5 mg/l chlorine.
David