IMO, if one of your concerns is leakage or water spillage, you are better off getting a reef ready tank (a tank that is drilled). I've heard of more stories about external overflows or HOB filters messing up and spilling onto the floor. Plus, it provides a nicer look, allows the use a sump (very valuable to hold your skimmer, reactors, fuge, etc.).
I have had a much easier time maintaining my 220G with a sump that holds my reactors, skimmer and a fuge area, than I have had with my 29G without a real sump area or skimmer.
I can't recommend a hang on back (HOB) filter, because I don't like them with tanks of the size you're looking at.