I guess no one knows. I can tell you that we use baby brine shrimp to feed our beta, Koi, Gold Fish, moly, platy and the rest of fresh water babbies. Since we already raise fresh water babbies and have new cultures of brine shrimp constantly being made over and over I did try to see if they would stay alive in the refugium or in the tank, but as of yet no luck, they seem to just die off or get eatten.